Searchable abstracts of presentations at key conferences in endocrinology

ea0092ps2-13-06 | Surgery | ETA2023

Prospective implementation of thyroid lobectomy recommendations and thyrospec molecular testing for bethesda III and IV nodules and impact on surgery

Yeo Caitlin , Wu Jiahui , Stewardson Paul , Eszlinger Markus , Paschke Ralf

Objectives: In May 2016, the local thyroid cancer tumor group proposed and adopted specific thyroid lobectomy recommendations based on the 2015 ATA guidelines. ThyroSPEC molecular testing was introduced for all Bethesda III and IV lesions in August 2020. The goal of this study was to evaluate the implementation of the ATA lobectomy guidelines and the introduction of ThyroSPEC molecular testing on rates of upfront total thyroidectomy (TTx), diagnostic lobectomy for Bethesda I-I...

ea0084op-12-60 | Oral Session 12: Nodules and Diagnostic | ETA2022

Population study on thyroid nodule ultrasound (TUS) reports quality with adherence to guidelines

Yang Hu Xun , Wu Jiahui , Seal Paula , Ghaznavi Sana , Symonds Christopher , Kinnear Susan , Paschke Ralf

Objectives: To date, there has been no population-wide data looking at the adherence to published TUS reporting guidelines for thyroid nodule malignancy risk assessment. In our health care region in 2018, two radiology groups worked closely with endocrinologists to improve the quality of their TUS reports by adhering to the 2015 ATA or the 2017 TIRADS guidelines. We aim to present the improvement in TUS reports quality with these dedicated changes.Method...

ea0092op-10-04 | Oral Session 10: Novel diagnostics in Thyroid cancer | ETA2023

Improvement in neck ultrasound report quality following implementation of ETA guidelines for postoperative cervical ultrasound for thyroid cancer follow-up, a prospective population study

Wu Jiahui , Yang Hu Xun , Seal Paula , Amin Parthiv , Paschke Ralf

Objective: We prospectively evaluated the quality of postoperative neck ultrasound (POU) for thyroid cancer patients in our healthcare region after the implementation of European Thyroid Association (ETA) guideline-based POU assessment with one radiology group in 2018.Methods: Our analysis involved 672 differentiated thyroid cancer (DTC) patients treated at our center between April 1, 2017, and March 1, 2023. POU report quality was compared between radio...

ea0092op-12-01 | Oral Session 12: Emerging Insights into Thyroid Cancer Genetics | ETA2023

Prospective evaluation of thyrospec molecular testing of indeterminate thyroid nodule cytologies following diagnostic pathway optimization

Stewardson Paul , Eszlinger Markus , Wu Jiahui , Khalil Moosa , J Demetrick Douglas , Cheung Winson , Box Adrian , Paschke Ralf

Objectives: Molecular diagnostic tests for indeterminate thyroid nodules (ITNs) are marketed based on negative predictive value (NPV) and benign call rate. Arguments that unnecessary surgeries are avoided based on NPV/BCR incorrectly assume that all ITNs would undergo diagnostic surgery in the absence of molecular testing. In our practice with centralized triage and cytopathology the resection and malignancy rate, respectively, were 21% and 26% for AUS/FLUS and 56% and 43% for...

ea0084op-09-46 | Oral Session 9: Thyroid Cancer Clinical | ETA2022

Interim outcome analysis of prospective ATA recurrence risk (RR) stratification for postoperative treatment and follow up of differentiated thyroid cancer (DTC)

Wu Jiahui , Yang Hu Xun , Ghaznavi Sana , Kinnear Susan , Symonds Christopher , Grundy Peter , Parkins Vicky , Sharma Priyanka , Lamb Debbie , Khalil Moosa , Hyrcza Martin , Chandarana Shamir , Pasieka Janice , Harvey Adrian , Warshawski Joseph , Hart Robert , Deutschman Michael , Randall Derrick , Paschke Ralf

Objective: The 2016 ATA RR assessment recommendations for patients with DTC were based on retrospective studies. We present the first outcomes of a prospective assessment of thyroid cancer management according to the ATA RR stratification.Methods: Using the Calgary prospective thyroid cancer database, we identified 612 patients with differentiated thyroid cancer (DTC) treated at our centre between April 2017 and December 2021. Each case was reviewed by t...